Oil-tea camellia (Camellia oleifera Abel) clone Cenruan 2 was selected and its seeds were sampled during the whole seed development stages from its initial development to seed drop. Their contents of major nutrients were determined during their whole development to analyze their dynamic change and their relation with seed germination rate. The results showed that with the development of the seeds, the seeds decreased their water content, increased their fat content, increased and then decreased the protein content, and decreased the content of total sugar and starch continuously. The oil content of the seeds at the mature stage was significantly negatively correlated the seed total sugar content, and negatively with starch content, but not significantly positively with protein content. The seed germination rate was significantly positively correlated with the seed oil rate, negatively with the seed total sugar but not significantly with starch and protein. It is best to harvest seeds of oi-tea cemellia during the period from mid-November to mid-December in the area where samples were collected, and the seeds can also be harvested in mid-October for seedling production.